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However, there is insufficient evidence indicating that holistic management of glycemia and other risk factors can alleviate the neuropathic pain
This review examines dysregulation of the KP in MDD, emphasizing KP metabolites particularly quinolinic acid and kynurenic acid as biomarkers and mediators of excitotoxicity, neuroinflammation, and oxidative stress, and discusses the therapeutic efficacy of antidepressants that modulate this pathway
Body Measurements, National Center for Health Statistics, CDC, accessed April 20, 2025, [70]
Obesity yes (PA, BMI 30+ with comorbidity)
Holding the dose at the current level for an extra four weeks is standard practice and does not reduce long-term outcomes
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